Eva Schmelz, PhC

Associate Professor

Graduate Program Faculty

Molecular and Cellular Science

Cancer prevention

Role of dietary and endogenous sphingolipids in cancer progression and metastasis: molecular mechanisms

Obesity and ovarian cancer

Enhanced contactless dielectrophoresis enrichment and isolation platform via cell-scale microstructures. Čemažar J, Douglas TA, Schmelz EM, Davalos RV.Biomicrofluidics. 2016 Jan 19;10(1):014109

Interleukin-12 Immunomodulation Delays the Onset of Lethal Peritoneal Disease of Ovarian Cancer. Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC.J Interferon Cytokine Res. 2016 Jan;36(1):62-73.

Ovarian tumor-initiating cells display a flexible metabolism. Anderson AS, Roberts PC, Frisard MI, Hulver MW, Schmelz EM.Exp Cell Res. 2014 Oct 15;328(1):44-57.

Targeting mitochondrial alterations to prevent type 2 diabetes--evidence from studies of dietary redox-active compounds. Cheng Z, Schmelz EM, Liu D, Hulver MW.Mol Nutr Food Res. 2014 Aug;58(8):1739-49.

Biomechanical profile of cancer stem-like/tumor-initiating cells derived from a progressive ovarian cancer model.Babahosseini H, Ketene AN, Schmelz EM, Roberts PC, Agah M.Nanomedicine. 2014 Jul;10(5):1013-9.

Investigating dielectric properties of different stages of syngeneic murine ovarian cancer cells. Salmanzadeh A, Sano MB, Gallo-Villanueva RC, Roberts PC, Schmelz EM, Davalos RV. Biomicrofluidics. 2013 Jan 23;7(1):11809.

Bioactive sphingolipid metabolites modulate ovarian cancer cell structural mechanics. Babahosseini H, Roberts PC, Schmelz EM, Agah M.Integr Biol (Camb). 2013 Nov;5(11):1385-92.

The parity-associated microenvironmental niche in the omental fat band is refractory to ovarian cancer metastasis. Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC. Cancer Prev Res (Phila). 2013 Nov;6(11):1182-93.

In vitro model of spontaneous mouse OSE transformation.Roberts PC, Schmelz EM. Methods Mol Biol. 2013;1049:393-408.

Intra-abdominal fat depots represent distinct immunomodulatory microenvironments: a murine model. Cohen CA, Shea AA, Heffron CL, Schmelz EM, Roberts PC. PLoS One. 2013 Jun 12;8(6):e66477.

Sphingolipid metabolites modulate dielectric characteristics of cells in a mouse ovarian cancer progression model.Salmanzadeh A, Elvington ES, Roberts PC, Schmelz EM, Davalos RV.Integr Biol (Camb). 2013 Jun;5(6):843-52.

Metabolic changes during ovarian cancer progression as targets for sphingosine treatment. Anderson AS, Roberts PC, Frisard MI, McMillan RP, Brown TJ, Lawless MH, Hulver MW, Schmelz EM. Exp Cell Res. 2013 Jun 10;319(10):1431-42

HNFE 4004 Seminar in HNFE: Writing and Discourse
HNFE 5144 Molecular Aspects of Nutrition and Disease
HNFE 5984 Molecular Biology Techniques

Chair-past, Research Interest Section Diet and Cancer, American Society for Nutrition, 2009-2010

Chair, Research Interest Section Diet and Cancer, American Society for Nutrition, 2008-2009

Recognized in ScienceNow, American Institute for Cancer Research newsletter, Summer 2008

Chair-Elect, Research Interest Section Diet and Cancer, American Society for Nutrition, 2007-2008

1996, Postdoctoral Fellowship, Emory University

1992, Ph.D., Nutrition and Human Biology, University of Giessen

1983, M.S., Human Nutrition, Justus-Liebig University

Eva Schmelz

40-231-3649
eschmelz@vt.edu

HNFE
1981 Kraft Drive
1011 ILSB
Blacksburg, VA 24060

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