Madlyn I. Frisard, PhD

Research Assistant Professor

Graduate Program Director

Graduate Program Faculty

Molecular and Cellular Science
Clinical Physiology and Metabolism

Skeletal muscle physiology and mitochondrial biology in obesity and metabolic disease; biological factors that influence adherence and outcomes in weight management

Last five years:

Beverage Choices of Adolescents and Their Parents Using the Theory of Planned Behavior: A Mixed Methods Analysis. Riebl SK, MacDougal C, Hill C, Estabrooks PA, Dunsmore JC, Savla J, Frisard MI, Dietrich AM, Davy BM. J Acad Nutr Diet. 2016 Feb;116(2):226-239.e1.

Isolation of Mitochondria from Minimal Quantities of Mouse Skeletal Muscle for High Throughput Microplate Respiratory Measurements. Boutagy NE, Pyne E, Rogers GW, Ali M, Hulver MW, Frisard MI. J Vis Exp. 2015 Nov 13;(105).

Using Isolated Mitochondria from Minimal Quantities of Mouse Skeletal Muscle for High throughput Microplate Respiratory Measurements. Boutagy NE, Rogers GW, Pyne ES, Ali MM, Hulver MW, Frisard MI. J Vis Exp. 2015 Oct 30;(105):e53216.

Probiotic supplementation attenuates increases in body mass and fat mass during high-fat diet in healthy young adults. Osterberg KL, Boutagy NE, McMillan RP, Stevens JR, Frisard MI, Kavanaugh JW, Davy BM, Davy KP, Hulver MW. Obesity (Silver Spring). 2015 Dec;23(12):2364-70

Metabolic endotoxemia with obesity: Is it real and is it relevant? Boutagy NE, McMillan RP, Frisard MI, Hulver MW. Biochimie. 2015 Jun 29. pii: S0300-9084(15)00199-6. doi: 10.1016/j.biochi.2015.06.020.

A systematic literature review and meta-analysis: The Theory of Planned Behavior's application to understand and predict nutrition-related behaviors in youth. Riebl SK, Estabrooks PA, Dunsmore JC, Savla J, Frisard MI, Dietrich AM, Peng Y, Zhang X, Davy BM.Eat Behav. 2015 Aug;18:160-78.

Selective overexpression of Toll-like receptor-4 in skeletal muscle impairs metabolic adaptation to high-fat feeding. McMillan RP, Wu Y, Voelker K, Fundaro G, Kavanaugh J, Stevens JR, Shabrokh E, Ali M, Harvey M, Anderson AS, Boutagy NE, Mynatt RL, Frisard MI, Hulver MW. Am J Physiol Regul Integr Comp Physiol. 2015 Aug 1;309(3):R304-13.

Early skeletal muscle adaptations to short-term high-fat diet in humans before changes in insulin sensitivity. Anderson AS, Haynie KR, McMillan RP, Osterberg KL, Boutagy NE, Frisard MI, Davy BM, Davy KP, Hulver MW. Obesity (Silver Spring). 2015 Apr;23(4):720-4

Angiotensin II receptor blockade and skeletal muscle metabolism in overweight and obese adults with elevated blood pressure. Boutagy NE, Marinik EL, McMillan RP, Anderson AS, Frisard MI, Davy BM, Rivero JM, Davy KP, Hulver MW. Ther Adv Cardiovasc Dis. 2015 Apr;9(2):45-50.

Low levels of lipopolysaccharide modulate mitochondrial oxygen consumption in skeletal muscle. Frisard MI, Wu Y, McMillan RP, Voelker KA, Wahlberg KA, Anderson AS, Boutagy N, Resendes K, Ravussin E, Hulver MW. Metabolism. 2015 Mar;64(3):416-27.

Ovarian tumor-initiating cells display a flexible metabolism. Anderson AS, Roberts PC, Frisard MI, Hulver MW, Schmelz EM. Exp Cell Res. 2014 Oct 15;328(1):44-57

Fiber hypertrophy and increased oxidative capacity can occur simultaneously in pig glycolytic skeletal muscle. Scheffler TL, Scheffler JM, Park S, Kasten SC, Wu Y, McMillan RP, Hulver MW, Frisard MI, Gerrard DE. Am J Physiol Cell Physiol. 2014 Feb 15;306(4):C354-63.

Social engagement and health in younger, older, and oldest-old adults in the Louisiana Healthy Aging Study. Cherry KE, Walker EJ, Brown JS, Volaufova J, LaMotte LR, Welsh DA, Su LJ, Jazwinski SM, Ellis R, Wood RH, Frisard MI. J Appl Gerontol. 2013 Feb;32(1):51-75

Metabolic changes during ovarian cancer progression as targets for sphingosine treatment. Anderson AS, Roberts PC, Frisard MI, McMillan RP, Brown TJ, Lawless MH, Hulver MW, Schmelz EM. Exp Cell Res. 2013 Jun 10;319(10):1431-42.

Angiotensin II receptor blockade and insulin sensitivity in overweight and obese adults with elevated blood pressure. Marinik EL, Frisard MI, Hulver MW, Davy BM, Rivero JM, Savla JS, Davy KP. Ther Adv Cardiovasc Dis. 2013 Feb;7(1):11-20

Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378*. Carrer M, Liu N, Grueter CE, Williams AH, Frisard MI, Hulver MW, Bassel-Duby R, Olson EN.Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15330-5

Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy. Liu N, Bezprozvannaya S, Shelton JM, Frisard MI, Hulver MW, McMillan RP, Wu Y, Voelker KA, Grange RW, Richardson JA, Bassel-Duby R, Olson EN. J Clin Invest. 2011 Aug;121(8):3258-68

Beverage Choices of Adolescents and Their Parents Using the Theory of Planned Behavior: A Mixed Methods Analysis. Riebl SK, MacDougal C, Hill C, Estabrooks PA, Dunsmore JC, Savla J, Frisard MI, Dietrich AM, Davy BM. J Acad Nutr Diet. 2016 Feb;116(2):226-239.e1

Isolation of Mitochondria from Minimal Quantities of Mouse Skeletal Muscle for High Throughput Microplate Respiratory Measurements. Boutagy NE, Pyne E, Rogers GW, Ali M, Hulver MW, Frisard MI. J Vis Exp. 2015 Nov 13;(105

Using Isolated Mitochondria from Minimal Quantities of Mouse Skeletal Muscle for High throughput Microplate Respiratory Measurements. Boutagy NE, Rogers GW, Pyne ES, Ali MM, Hulver MW, Frisard MI. J Vis Exp. 2015 Oct 30;(105):e53216.

Probiotic supplementation attenuates increases in body mass and fat mass during high-fat diet in healthy young adults. Osterberg KL, Boutagy NE, McMillan RP, Stevens JR, Frisard MI, Kavanaugh JW, Davy BM, Davy KP, Hulver MW. Obesity (Silver Spring). 2015 Dec;23(12):2364-70

Metabolic endotoxemia with obesity: Is it real and is it relevant? Boutagy NE, McMillan RP, Frisard MI, Hulver MW. Biochimie. 2015 Jun 29. pii: S0300-9084(15)00199-6.

A systematic literature review and meta-analysis: The Theory of Planned Behavior's application to understand and predict nutrition-related behaviors in youth. Riebl SK, Estabrooks PA, Dunsmore JC, Savla J, Frisard MI, Dietrich AM, Peng Y, Zhang X, Davy BM. Eat Behav. 2015 Aug;18:160-78.

Selective overexpression of Toll-like receptor-4 in skeletal muscle impairs metabolic adaptation to high-fat feeding. McMillan RP, Wu Y, Voelker K, Fundaro G, Kavanaugh J, Stevens JR, Shabrokh E, Ali M, Harvey M, Anderson AS, Boutagy NE, Mynatt RL, Frisard MI, Hulver MW. Am J Physiol Regul Integr Comp Physiol. 2015 Aug 1;309(3):R304-13.

Early skeletal muscle adaptations to short-term high-fat diet in humans before changes in insulin sensitivity. Anderson AS, Haynie KR, McMillan RP, Osterberg KL, Boutagy NE, Frisard MI, Davy BM, Davy KP, Hulver MW. Obesity (Silver Spring). 2015 Apr;23(4):720-4

Angiotensin II receptor blockade and skeletal muscle metabolism in overweight and obese adults with elevated blood pressure. Boutagy NE, Marinik EL, McMillan RP, Anderson AS, Frisard MI, Davy BM, Rivero JM, Davy KP, Hulver MW. Ther Adv Cardiovasc Dis. 2015 Apr;9(2):45-50.

Low levels of lipopolysaccharide modulate mitochondrial oxygen consumption in skeletal muscle. Frisard MI, Wu Y, McMillan RP, Voelker KA, Wahlberg KA, Anderson AS, Boutagy N, Resendes K, Ravussin E, Hulver MW. Metabolism. 2015 Mar;64(3):416-27.

Ovarian tumor-initiating cells display a flexible metabolism. Anderson AS, Roberts PC, Frisard MI, Hulver MW, Schmelz EM. Exp Cell Res. 2014 Oct 15;328(1):44-57.

Fiber hypertrophy and increased oxidative capacity can occur simultaneously in pig glycolytic skeletal muscle. Scheffler TL, Scheffler JM, Park S, Kasten SC, Wu Y, McMillan RP, Hulver MW, Frisard MI, Gerrard DE. Am J Physiol Cell Physiol. 2014 Feb 15;306(4):C354-63.

Social engagement and health in younger, older, and oldest-old adults in the Louisiana Healthy Aging Study. Cherry KE, Walker EJ, Brown JS, Volaufova J, LaMotte LR, Welsh DA, Su LJ, Jazwinski SM, Ellis R, Wood RH, Frisard MI. J Appl Gerontol. 2013 Feb;32(1):51-75.

Metabolic changes during ovarian cancer progression as targets for sphingosine treatment. Anderson AS, Roberts PC, Frisard MI, McMillan RP, Brown TJ, Lawless MH, Hulver MW, Schmelz EM. Exp Cell Res. 2013 Jun 10;319(10):1431-42.

Angiotensin II receptor blockade and insulin sensitivity in overweight and obese adults with elevated blood pressure. Marinik EL, Frisard MI, Hulver MW, Davy BM, Rivero JM, Savla JS, Davy KP. Ther Adv Cardiovasc Dis. 2013 Feb;7(1):11-20.

Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378*. Carrer M, Liu N, Grueter CE, Williams AH, Frisard MI, Hulver MW, Bassel-Duby R, Olson EN. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15330-5.

Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy. Liu N, Bezprozvannaya S, Shelton JM, Frisard MI, Hulver MW, McMillan RP, Wu Y, Voelker KA, Grange RW, Richardson JA, Bassel-Duby R, Olson EN. J Clin Invest. 2011 Aug;121(8):3258-68.
 

HNFE 4004: Writing and Discourse

HNFE 5044: Seminar in Nutrition and Foods

2005, Ph.D., Exercise Physiology, Louisiana State University
1999, M.S., Clinical Exercise Physiology, Louisiana State University
1997, B.A., Kinesiology, Louisiana State University

Madlyn Frisard

540-231-9994
frisardm@vt.edu
HNFE
225 Wallace Hall
Blacksburg, VA 24060

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