1992 Marietta College, BA, Fitness Management
1998 McDaniel College, MS, Exercise Science
2001 University of Kansas, PhD, Exercise Physiology
2004 East Carolina, Postdoctoral, Physiology
To better understand the nutritional signals that contribute to dysregulated skeletal muscle substrate metabolism in disease states such as obesity, type 2 diabetes, and cancer. We are studying the role of pro-inflammatory pathways in skeletal muscle lipid accumulation, and how the activity of these pathways is exacerbated by over-nutrition.
Metabolic changes during ovarian cancer progression as targets for sphingosine treatment. Anderson AS, Roberts PC, Frisard MI, McMillan RP, Brown TJ, Lawless MH, Hulver MW, Schmelz EM.Exp Cell Res. 2013 Jun 10;319(10):1431-42. doi: 10.1016/j.yexcr.2013.02.017.
Angiotensin II receptor blockade and insulin sensitivity in overweight and obese adults with elevated blood pressure.Marinik EL, Frisard MI, Hulver MW, Davy BM, Rivero JM, Savla JS, Davy KP. Ther Adv Cardiovasc Dis. 2013 Feb;7(1):11-20.
Chronic administration of dietary grape seed extract increases colonic expression of gut tight junction protein occludin and reduces fecal calprotectin: a secondary analysis of healthy Wistar Furth rats. Goodrich KM, Fundaro G, Griffin LE, Grant A, Hulver MW, Ponder MA, Neilson AP. Nutr Res. 2012 Oct;32(10):787-94. doi: 10.1016/j.nutres.2012.09.004.
Regulation of Insulin and Leptin Signaling by Muscle Suppressor of Cytokine Signaling 3 (SOCS3).Yang Z, Hulver MW, McMillan RP, Cai L, Kershaw EE, Yu L, Xue B, Shi HPLoS One. 2012;7(10):e47493. doi: 10.1371/journal.pone.0047493. .
Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378.Carrer M, Liu N, Grueter CE, Williams AH, Frisard MI, Hulver MW, Bassel-Duby R, Olson EN.Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15330-5.
Mex3c mutation reduces adiposity and increases energy expenditure.Jiao Y, George SK, Zhaoq Q, Hulver MW, Hutson SM, Bishop CE, Lu B.Mol Cell Biol. 2012 Aug 27.
Fish oil and indomethacin in combination potently reduce dyslipidemia and hepatic steatosis in LDLR -/- mice.Murali G, Milne GL, Webb CD, Stewart AB, McMillan RP, Lyle BC, Hulver MW, Saraswathi V.J Lipid Res. 2012 Oct;53(10):2186-97.
Effects of the insulin sensitizing drug, pioglitazone, and lipopolysaccharide administration on markers of systemic inflammation and clinical parameters in horses.Wearn JG, Suagee JK, Crisman MV, Corl BA, Hulver MW, Hodgson DR, Geor RJ, McCutcheon LJ.Vet Immunol Immunopathol. 2012 Jan 15;145(1-2):42-9.
Resistance exercise and aerobic exercise when paired with dietary energy restriction both reduce the clinical components of metabolic syndrome in previously physically inactive males.Potteiger JA, Claytor RP, Hulver MW, Hughes MR, Carper MJ, Richmond S, Thyfault JP.Eur J Appl Physiol. 2012 Jun;112(6):2035-44.