Role of bHLH transcription factors in hypothalamic gene expression, especially in the regulation of body weight, exercise and motivation; the use of transgenic and knockout animals, and phylogenetic analysis of gene and allele evolution, as these relate to body weight control and human health.
Goswami RS, Atenafu EG, Xuan Y, Waldron L, Reis PP, Sun T, Datti A, Xu W, Kuruvilla J, Good DJ, Lai R, Church AJ, Lam WS, Baetz T, Lebrun DP, Sehn LH, Farinha P, Jurisica I, Bailey DJ, Gascoyne RD, Crump M, Kamel-Reid S. MicroRNA signature obtained from the comparison of aggressive with indolent non-Hodgkin lymphomas: potential prognostic value in mantle-cell lymphoma. Journal of Clinical Oncology. 2013 Aug 10;31(23):2903-11. doi: 10.1200/JCO.2012.45.3050.
Good DJ, Braun T. NHLH2: at the intersection of obesity and fertility. Trends Endocrinol Metab. 2013 Aug;24(8):385-90. doi: 10.1016/j.tem.2013.04.003. Epub 2013 May 17.
Al Rayyan N, Wankhade UD, Bush K, Good DJ. Two single nucleotide polymorphisms in the human nescient helix-loop-helix 2 (NHLH2) gene reduce mRNA stability and DNA binding. Gene. 2013 Jan 1;512(1):134-42. doi: 10.1016/j.gene.2012.09.068.
Good, D.J., McIntyre, C.M., and Marchant, M.A. (2012) The USDA Scholars Program: Innovations in a Summer Undergraduate Research Program, NACTA Journal.
Kim, J-H, Park, Y., Kim, D., Good, D.J.and Park, Y., (2012) Dietary Conjugated Nonadecadienoic Acid Prevents Adult-onset Obesity in Nescient Basic Helix-Loop-Helix 2 Knockout Mice, J. Nutritional Biochemistry.
Kim, J-H., Gilliard, D., Good, D.J., and Park, Y., (2012) Preventive effects of conjugated linoleic acid on obesity by improved physical activity in nescient basic helix-loop-helix 2 knockout mice during growth period, Food and Function, 3: 1280-1285.
Al_Rayyan, N., Wankhade, U.D., Bush, K., and Good, D.J. (2012) Two Single Nucleotide Polymorphisms in the Human Nescient Helix Loop Helix 2 (NHLH2) Gene Reduce mRNA Stability and DNA Binding, Gene, 512: 134-142.
Good, D.J. (2012) Extending the Reach of Exendin-4: New Pathways in the Control of Body Weight and Glucose Homeostasis, Endocrinology, 153: 2051-2053
Davis, G., Jacob J. and Good, D.J. (2012) Effects of Price and Genetics on Food Choices and Obesity-Related Phenotypes in Mice, Open Neuroendocrinology Journal, 5:13-21 (Open source journal)
Wankhade, U.D. and Good, D.J. (2011) Melanocortin 4 Receptor is a Transcriptional Target of Nescient Helix-Loop-Helix-2, Molecular and Cellular Endocrinology, 341: 39-47
Zhang, H. and Good, D.J. (2011) Comparison of Hypothalamic mRNA Levels in Animals Euthanized by CO2 Asphyxiation or Focused-Beam Microwave Irradiation, Lab Animal,40: 313-318